Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249001 | 0.89 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL28266453 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL5370015 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL9240061 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL3136218 | 0.82 | P2RX7 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL30066901 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL5380872 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL28599443 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL28138447 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL8440245 | 0.78 | MTNR1A (0.48) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121562-B | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113121562-A | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113105475-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-109071563-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-0380063-B1 | 1,2-CYCLOHEXYLAMINOARYL AMIDES USEFUL AS ANALGESIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-07-21 | — | — | EP | disclosed |
| US-5019588-A | Nonhabit-forming analgeiscs | WARNER-LAMBERT COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0380063-A1 | 1,2-cyclohexylaminoaryl amides useful as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4906655-A | Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |