Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515637 | 0.95 | EPHX2 (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515897 | 0.89 | EGFR (0.42) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515974 | 0.89 | HIF1A (0.39) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9518022 | 0.88 | HDAC6 (0.39) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515550 | 0.88 | MEN1 (0.36) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515528 | 0.86 | LMNA (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9519314 | 0.85 | EGFR (0.37) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9516131 | 0.85 | GABRA5 (0.40) | GAAGABRA5 | |
| SCHEMBL9519674 | 0.84 | EGFR (0.43) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9516279 | 0.83 | HIF1A (0.39) | HDAC6HDAC3HDAC1HDAC2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |