Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516716 | 0.95 | EPHX2 (0.36) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9517030 | 0.89 | SLC6A9 (0.39) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9518016 | 0.88 | MEN1 (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515431 | 0.88 | PNMT (0.41) | HDAC6HDAC5CES2HDAC3HDAC1 | |
| SCHEMBL9515528 | 0.84 | LMNA (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9519314 | 0.84 | EGFR (0.37) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9519439 | 0.83 | PNMT (0.42) | HDAC6HDAC5CES2HDAC3HDAC1 | |
| SCHEMBL9515637 | 0.83 | EPHX2 (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515897 | 0.82 | EGFR (0.42) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9515974 | 0.81 | HIF1A (0.39) | MEN1NPC1RAB9AKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |