Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435626 | 0.75 | PDE3B (0.43) | PDE3BPDE3ANOTUMKCNH2CA1 | |
| SCHEMBL9518264 | 0.74 | ALDH1A1 (0.32) | PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL10543233 | 0.74 | ALDH1A1 (0.34) | PDE3BPDE3A | |
| SCHEMBL4423214 | 0.73 | RXRA (0.45) | PDE3BPDE3ANOTUM | |
| SCHEMBL4429082 | 0.72 | NOTUM (0.60) | PDE3BPDE3ANOTUM | |
| SCHEMBL6155424 | 0.71 | CYP4F2 (0.36) | — | |
| SCHEMBL4425470 | 0.71 | PDE3B (0.47) | PDE3BPDE3ANOTUMCA1CA2 | |
| SCHEMBL4427890 | 0.69 | NOTUM (0.55) | PDE3BPDE3ANOTUM | |
| SCHEMBL4429999 | 0.68 | RXRA (0.41) | PDE3BPDE3ANOTUMKCNH2 | |
| SCHEMBL6189927 | 0.66 | PTGS2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |