Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612453 | 0.85 | PARP1 (0.42) | HIF1AEPAS1ALOX15ALOX12TSHR | |
| SCHEMBL6155424 | 0.84 | CYP4F2 (0.36) | ALOX15ALOX12TSHR | |
| SCHEMBL6189927 | 0.81 | PTGS2 (0.38) | ALOX15ALOX12 | |
| SCHEMBL5534700 | 0.81 | HIF1A (0.32) | HIF1AEPAS1ALOX15ALOX12TSHR | |
| SCHEMBL828814 | 0.78 | FAAH (0.39) | TSHR | |
| Acetic Acid SCHEMBL5482093 | 0.78 | KDM4E (0.38) | ALOX15ALOX12 | |
| SCHEMBL27545532 | 0.77 | MAOB (0.31) | MAOB | |
| SCHEMBL13018533 | 0.77 | CTSB (0.42) | — | |
| SCHEMBL10257181 | 0.76 | MMP12 (0.38) | ALOX12TSHR | |
| SCHEMBL19143726 | 0.76 | ALOX15 (0.39) | HIF1AEPAS1ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |