Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418269 | 0.88 | TP53 (0.44) | ALDH1A1CYP3A4TSHRHSD17B10CA1 | |
| SCHEMBL9721980 | 0.84 | ALDH1A1 (0.35) | ADRA1AIDO1ALDH1A1TDP1TSHR | |
| SCHEMBL9722105 | 0.83 | TSHR (0.46) | ALDH1A1TSHRLMNARXRAPTGS1 | |
| SCHEMBL23027463 | 0.75 | ADRA1A (0.35) | ADRA1AALDH1A1CYP3A4MAOAPTGS1 | |
| SCHEMBL18053266 | 0.74 | HTR5A (0.46) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL6874731 | 0.72 | TP53 (0.42) | ALDH1A1CYP3A4RXRARARARARB | |
| SCHEMBL4655427 | 0.72 | CD274 (0.36) | IDO1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9358367 | 0.72 | HTR5A (0.44) | ALDH1A1TDP1LMNAADRA2BPTGS1 | |
| SCHEMBL23027378 | 0.71 | ALDH1A1 (0.36) | ADRA1AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL23023377 | 0.71 | HTR5A (0.46) | ALDH1A1TDP1LMNAACHEADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382076-B1 | PHENYLHYDRAZONES, THEIR PREPARATION AND MEDICAMENTS AND COSMETICS MANUFACTURED THEREFROM | BASF Aktiengesellschaft (DE) | 1993-01-20 | — | — | EP | disclosed |
| US-5158977-A | Antioxidant; preventive treatment of cutaneous inflammations and allergies | L'OREAL (FR) | 1992-10-27 | — | — | US | disclosed |
| US-5072042-A | Skin disorders, anticarcinogenic-antitumor agent | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| US-5043482-A | New derivatives of 5,6,7,8-tetrahydro-1-naphthalenol, a process for their preparation and cosmetic and pharmaceutical compositions containing them | L'OREAL (FR) | 1991-08-27 | — | — | US | disclosed |
| EP-0382076-A1 | Phenylhydrazones, their preparation and medicaments and cosmetics manufactured therefrom | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |