Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200278 | 0.85 | CRHBP (0.43) | MAPTCRHBPCRHR2KDM4ELMNA | |
| SCHEMBL2724523 | 0.82 | NPSR1 (0.46) | SMN1; SMN2CRHBPCRHR2LMNAMTNR1A | |
| SCHEMBL27667245 | 0.80 | KMT2A (0.49) | KMOMAPTSMN1; SMN2MGLLCRHBP | |
| SCHEMBL31022685 | 0.79 | CA12 (0.46) | KMOMAPTKDM4ELMNA | |
| SCHEMBL2113104 | 0.79 | CA12 (0.46) | KMOMAPTKDM4ELMNA | |
| SCHEMBL27819349 | 0.78 | ALDH1A1 (0.53) | MAPTCRHBPCRHR2KDM4ELMNA | |
| SCHEMBL3150723 | 0.78 | LMNA (0.51) | MAPTSMN1; SMN2KDM4ELMNAPKM | |
| SCHEMBL3158471 | 0.78 | HTR3E (0.47) | MAPTSMN1; SMN2LMNA | |
| SCHEMBL8426828 | 0.74 | KMT2A (0.44) | MAPTSMN1; SMN2CRHBPCRHR2LMNA | |
| SCHEMBL9761964 | 0.74 | PARP1 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397556-B1 | N-Phenyl amides, methods for their preparation and medicaments containing them | RHONE POULENC SANTE (FR) | 1993-10-20 | — | — | EP | disclosed |
| EP-0397556-A1 | N-Phenyl amides, methods for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-11-14 | — | — | EP | disclosed |