Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 4/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193393 | 0.77 | KAT2B (0.60) | KAT2BG6PDALDH1A1KDM4EMAPT | |
| SCHEMBL9135607 | 0.72 | KAT2B (0.70) | KAT2BG6PDMGLLALDH1A1KDM4E | |
| SCHEMBL2108805 | 0.70 | KAT2B (0.73) | KAT2BMAPTCA12CA1CA9 | |
| SCHEMBL7623894 | 0.69 | KAT2B (0.67) | KAT2BG6PDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8373401 | 0.68 | G6PD (0.72) | G6PDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12632651 | 0.67 | KAT2B (0.61) | KAT2BG6PDALDH1A1KDM4EMAPT | |
| SCHEMBL24034719 | 0.65 | MGLL (0.62) | MGLLALDH1A1KDM4EMAPTALOX5 | |
| SCHEMBL9854210 | 0.65 | KAT2B (0.50) | KAT2BALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL80967 | 0.64 | KAT2B (0.58) | KAT2BG6PDMGLLALDH1A1MAPT | |
| SCHEMBL21887490 | 0.63 | KAT2B (0.56) | KAT2BALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |