Phosphoric Acid

Phosphoric Acid

SCHEMBL9519019

CNC(CCc1cccc2ccccc12)c1ccccc1.CNC(CCc1cccc2ccccc12)c1ccccc1.CNC(CCc1cccc2ccccc12)c1ccccc1.O=P(O)(O)O

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRD1 known ✓ P41143 1/20 0.40
OPRK1 known ✓ P41145 1/20 0.40
ACP3 P15309 1/20 0.47
MTNR1A P48039 3/20 0.46
KMT2A Q03164 2/20 0.43
ECE1 P42892 2/20 0.42
MME P08473 1/20 0.42
NQO2 P16083 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
SLC6A4 P31645 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP14 P50281 1/20 0.39
CTNNB1 P35222 1/20 0.39
MTNR1B P49286 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9519025 1.00 ACP3 (0.47) ACP3MTNR1AKMT2AECE1MME
SCHEMBL10484309 0.83 SIGMAR1 (0.49) MTNR1AKMT2ANQO2SLC6A4SIGMAR1
Oxalic Acid SCHEMBL9517875 0.83 KMT2A (0.51) MTNR1AKMT2ATDP1OPRD1OPRK1
Oxalic Acid SCHEMBL9517878 0.83 KMT2A (0.51) MTNR1AKMT2ATDP1OPRD1OPRK1
Cadaverine Tartrate SCHEMBL9518010 0.80 MTNR1A (0.45) MTNR1AKMT2ATDP1OPRD1OPRK1
Cadaverine Tartrate SCHEMBL9518009 0.80 MTNR1A (0.45) MTNR1AKMT2ATDP1OPRD1OPRK1
Phosphoric Acid SCHEMBL9613715 0.79 KMT2A (0.52) KMT2ATDP1SLC6A4
Hydrochloric Acid SCHEMBL9520766 0.75 MC4R (0.47) MTNR1ASLC6A4SIGMAR1
SCHEMBL9859583 0.72 SIGMAR1 (0.48) KMT2ANQO2TDP1SLC6A4SIGMAR1
SCHEMBL30849686 0.72 TDP1 (0.47) ACP3MTNR1AKMT2ATDP1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0318234-B1 IMPROVEMENTS IN OR RELATING TO SELECTIVE SEROTONIN UPTAKE INHIBITORS ELI LILLY AND COMPANY (US) 1993-03-17 EP disclosed
US-4876282-A ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT ELI LILLY AND COMPANY (US) 1989-10-24 US disclosed
EP-0318234-A2 Improvements in or relating to selective serotonin uptake inhibitors ELI LILLY AND COMPANY (US) 1989-05-31 EP disclosed