Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.34 |
| ▸ | TK2 | O00142 | 3/20 | 0.34 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053437 | 0.85 | TK1 (0.42) | TK2TK1LMNA | |
| SCHEMBL7262195 | 0.84 | PYGM (0.36) | PYGMTK2TK1LMNASMN1; SMN2 | |
| SCHEMBL6829048 | 0.84 | PYGM (0.36) | PYGMTK2TK1LMNASMN1; SMN2 | |
| SCHEMBL11880667 | 0.79 | TK2 (0.35) | PYGMTK2TK1 | |
| SCHEMBL121731 | 0.76 | SLC28A1 (0.47) | — | |
| SCHEMBL7872134 | 0.75 | PYGB (0.31) | PYGM | |
| SCHEMBL22345897 | 0.75 | TK1 (0.40) | TK2TK1LMNA | |
| SCHEMBL6826273 | 0.75 | TK2 (0.36) | PYGMTK2TK1 | |
| SCHEMBL27900812 | 0.75 | PYGM (0.33) | PYGM | |
| SCHEMBL4595273 | 0.75 | PYGM (0.35) | PYGMTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025872-A | Minor groove binder (MGB)-oligonucleotide miRNA antagonists | ELITECH HOLDING BV | 2013-04-03 | — | — | CN | claimed |
| CN-107109407-A | compositions and methods for treating amyotrophic lateral sclerosis (ALS) | 沃雅戈治疗公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103228796-A | Genotyping dna | CELULA INC | 2013-07-31 | — | — | CN | disclosed |
| CN-103068981-A | Sirna targeting VEGFA and methods for treatment in VIVO | ALCON RES LTD | 2013-04-24 | — | — | CN | disclosed |
| CN-103025872-A | Minor groove binder (MGB)-oligonucleotide miRNA antagonists | ELITECH HOLDING BV | 2013-04-03 | — | — | CN | disclosed |
| CN-101107352-B | Apparatus and system having dry gene silencing compostions | DHARMACON INC | 2013-03-20 | — | — | CN | disclosed |
| CN-102282155-A | Method for the synthesis of phosphorus atom modified nucleic acids | — | 2011-12-14 | — | — | CN | disclosed |
| CN-101107352-A | Apparatus and system having dry gene silencing pools | DHARMACON INC (US) | 2008-01-16 | — | — | CN | disclosed |
| EP-0506892-A4 | BORONATED NUCLEOSIDES | — | 1993-03-31 | — | — | EP | disclosed |
| EP-0506892-A1 | BORONATED NUCLEOSIDES. | BORON BIOLOG INC (US) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991009048-A1 | BORONATED NUCLEOSIDES | BARON BIOLOGICALS, INC. (US) | 1991-06-27 | — | — | WO | disclosed |