SCHEMBL7872134

SCHEMBL7872134

CNc1cn([C@]2(C)O[C@H](CO)[C@@H](O)[C@H]2O)c(=[Se])[nH]c1=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PYGB P11216 2/20 0.31
PYGM P11217 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262195 0.88 PYGM (0.36) PYGM
SCHEMBL27900812 0.86 PYGM (0.33) PYGBPYGM
SCHEMBL28284460 0.86
SCHEMBL28230285 0.84 PYGB (0.34) PYGBPYGM
SCHEMBL28326624 0.76 PYGM (0.34) PYGM
SCHEMBL9519057 0.75 PYGM (0.34) PYGM
SCHEMBL8804692 0.75 PYGB (0.32) PYGBPYGM
SCHEMBL547489 0.75 TYMP (0.33) PYGM
SCHEMBL513129 0.73 PYGL (0.31) PYGBPYGM
SCHEMBL1825757 0.72 TK1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104114572-A Modified nucleosides, nucleotides and nucleic acid compositions MODERNA THERAPEUTICS INC 2014-10-22 CN disclosed
CN-103179984-A Pegylated liposomes for delivery of immunogen-encoding RNA NOVARTIS AG 2013-06-26 CN disclosed
CN-103052400-A Virus-like delivery particles for self-replicating RNA molecules NOVARTIS AG 2013-04-17 CN disclosed
CN-102947450-A RNA preparation comprising purified modified RNA for reprogramming cells KARIKO KATALIN 2013-02-27 CN disclosed
US-6303295-B1 APPARATUS FOR THE DIAGNOSIS AND TREATMENT OF VIRAL INFECTION; FOR TREATMENT OF CANCER; FOR USE IN GENE THERAPY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2001-10-16 US disclosed