SCHEMBL9519142

SCHEMBL9519142

O=C(O)C[S+]([O-])Cc1ccco1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
TAS2R14 Q9NYV8 1/20 0.41
ALOX5 P09917 1/20 0.40
MAPT P10636 1/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 1/20 0.39
EPHX2 P34913 3/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
ERCC5 P28715 1/20 0.38
FEN1 P39748 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
ATM Q13315 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6433645 0.85 ALOX5 (0.46) ALDH1A1TAS2R14ALOX5MAPTHSD17B10
SCHEMBL9083176 0.85 ALDH1A1 (0.40) ALDH1A1TAS2R14ALOX5MAPTTSHR
SCHEMBL23124452 0.81 ALDH1A1 (0.44) ALDH1A1MAPTTSHRTDP1L3MBTL1
SCHEMBL9194241 0.81 HSD17B10 (0.51) ALDH1A1TAS2R14MAPTTSHRHSD17B10
SCHEMBL10526899 0.79 TSHR (0.46) ALDH1A1MAPTTSHRHSD17B10HPGD
SCHEMBL17038874 0.76 ALDH1A1 (0.45) ALDH1A1ALOX5MAPTHSD17B10EPHX2
SCHEMBL3324604 0.74 POLB (0.55) ALDH1A1MAPTTSHREPHX2MEN1
SCHEMBL8445238 0.72 POLB (0.40) ALDH1A1ALOX5MAPTHSD17B10EPHX2
SCHEMBL25097667 0.72 ALDH1A1 (0.39) ALDH1A1ALOX5MAPTHSD17B10TDP1
SCHEMBL17035939 0.72 RIPK1 (0.39) ALDH1A1ALOX5MAPTTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4293076-B1 SELF-HEALING RUBBER COMPRISING A POLY(GLYCEROLMONOMETHACRYLATE) BORONIC ESTER COMPLEX BRIDGESTONE CORP (JP) 2025-04-02 EP claimed
EP-3587859-B1 TRANSMISSION BELT MITSUBOSHI BELTING LTD (JP) 2024-12-18 EP claimed
EP-3822510-B1 FRICTION TRANSMISSION BELT BANDO CHEMICAL IND (JP) 2022-09-07 EP claimed
EP-4363466-B1 PROCESSING OPTIMIZED REACTIVE POLYMER COMPOSITION CLARIANT INT LTD (CH) 2025-04-09 EP disclosed
EP-4363466-A1 PROCESSING-OPTIMIZED, REACTIVE POLYMER COMPOSITION Clariant International Ltd (CH) 2024-05-08 EP disclosed
US-20230000773-A1 NOVEL HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2023-01-05 US disclosed
WO-2023274706-A1 PROCESSING-OPTIMIZED, REACTIVE POLYMER COMPOSITION CLARIANT INTERNATIONAL LTD (CH) 2023-01-05 WO disclosed
US-20230000773-A1 NOVEL HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2023-01-05 US disclosed
EP-4112660-A1 PROCESSING OPTIMIZED REACTIVE POLYMER COMPOSITION Clariant International Ltd (CH) 2023-01-04 EP disclosed
EP-3781622-B1 ADHESIVE COMPOSITIONS WITH A GELCONTENT FROM CROSSLINKING OF KETO- OR ALDEHYDE GROUPS BASF SE (DE) 2022-10-12 EP disclosed
EP-4031527-A1 HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2022-07-27 EP disclosed
WO-2021055849-A1 HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2021-03-25 WO disclosed
WO-2021055849-A1 HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2021-03-25 WO disclosed
EP-0282077-B1 Pyridyloxy derivatives FUJIREBIO KK (JP) 1993-11-10 EP disclosed
US-4988828-A Antiulcer agents, antagonist for histamine H2 receptors FUJIREBIO KABUSHIKI KAISHA (JP) 1991-01-29 US disclosed
US-4977267-A ANTISECRETORY AGENT FUJIREBIO KABUSHIKI KAISHA (JP) 1990-12-11 US disclosed
US-4912101-A Containing a secondary amide, suflur group and a furan ring FUJIREBIO KABUSHIKI KAISHA (JP) 1990-03-27 US disclosed
US-4837316-A ANTIULCER AGENTS FUJIREBIO KABUSHIKI KAISHA (JP) 1989-06-06 US disclosed
EP-0318036-A2 Phenoxypropyl derivatives FUJIREBIO KABUSHIKI KAISHA (JP) 1989-05-31 EP disclosed
EP-0282077-A2 Pyridyloxy derivatives FUJIREBIO KABUSHIKI KAISHA (JP) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000773-A1 NOVEL HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PEBP1, PLTP ALDH1A1 4749/4885TAS2R14 3435/4885ALOX5 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.