Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 13/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 12/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566866 | 0.89 | KDM4E (0.56) | P4HTMLMNASTAT3SMN1; SMN2ALDH1A1 | |
| SCHEMBL9566751 | 0.88 | NPC1 (0.52) | P4HTMLMNASTAT3SMN1; SMN2ALDH1A1 | |
| SCHEMBL9566868 | 0.88 | CXCR2 (0.60) | CXCR2CXCR1P4HTMALDH1A1 | |
| SCHEMBL9566798 | 0.87 | MAPT (0.60) | P4HTMLMNASTAT3SMN1; SMN2ALDH1A1 | |
| SCHEMBL9566753 | 0.85 | CXCR2 (0.54) | CXCR2CXCR1P4HTMLMNAALDH1A1 | |
| SCHEMBL9566902 | 0.83 | CXCR2 (0.62) | CXCR2CXCR1P4HTMALDH1A1 | |
| SCHEMBL9566842 | 0.82 | SENP7 (0.53) | P4HTMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9566796 | 0.82 | LMNA (0.56) | P4HTMFAAHLMNASTAT3SMN1; SMN2 | |
| SCHEMBL9566786 | 0.81 | CXCR2 (0.57) | CXCR2CXCR1P4HTMALDH1A1 | |
| SCHEMBL9566779 | 0.81 | TP53 (0.55) | P4HTMLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |