Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209203 | 0.78 | MAPT (0.69) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL9521395 | 0.74 | ADRA1A (0.41) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL9521689 | 0.73 | POLB (0.45) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL9521622 | 0.73 | TRPV4 (0.43) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9521170 | 0.72 | SMN1; SMN2 (0.50) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL9674557 | 0.71 | ADRA1A (0.59) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL3276446 | 0.71 | ALDH1A1 (0.58) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL3276441 | 0.71 | ALDH1A1 (0.58) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL21568085 | 0.70 | ALDH1A1 (0.67) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL9706750 | 0.69 | NAPRT (0.42) | MAPTALDH1A1RAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
| EP-0366614-A2 | Pharmaceutically active dithioketene derivatives | YUHAN CORPORATION, LTD. (KR) | 1990-05-02 | — | — | EP | disclosed |