Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.30 |
| ▸ | HTR3B | O95264 | 2/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520464 | 0.91 | HTR3A (0.35) | MAPTTSHRHTR3AKMT2AMEN1 | |
| SCHEMBL9521255 | 0.88 | HPGD (0.37) | MAPTHTR3AKMT2AMEN1HPGD | |
| SCHEMBL9521366 | 0.88 | HTR3A (0.31) | MAPTTSHRHTR3A | |
| SCHEMBL9522986 | 0.87 | MAPT (0.38) | MAPTKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL9521382 | 0.87 | MAPT (0.38) | MAPTKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL9523079 | 0.84 | MEN1 (0.33) | MAPTKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL22745804 | 0.81 | MAPT (0.36) | MAPTKMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL9521287 | 0.79 | HTR3A (0.33) | MAPTTSHRHTR3AKMT2AMEN1 | |
| SCHEMBL9468954 | 0.79 | MAPT (0.35) | MAPTKMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL9521057 | 0.78 | GAA (0.38) | MAPTHTR3AHPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |