Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520873 | 0.90 | MEN1 (0.33) | MEN1KMT2AGUSBBAZ2BBAZ2A | |
| SCHEMBL9521362 | 0.86 | HTR7 (0.40) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL9520592 | 0.84 | MAPT (0.32) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9521057 | 0.84 | GAA (0.38) | GUSBBAZ2BBAZ2AGAALMNA | |
| SCHEMBL10410194 | 0.83 | MEN1 (0.35) | MEN1KMT2AGUSBBAZ2BBAZ2A | |
| SCHEMBL9520464 | 0.79 | HTR3A (0.35) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL9521255 | 0.78 | HPGD (0.37) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL22745804 | 0.78 | MAPT (0.36) | KMT2AGUSBBAZ2BBAZ2AGAA | |
| SCHEMBL9522986 | 0.78 | MAPT (0.38) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9521382 | 0.78 | MAPT (0.38) | MEN1KMT2AMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |