Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213208 | 0.79 | HMGCR (0.31) | ALDH1A1 | |
| SCHEMBL3894280 | 0.72 | ALOX5AP (0.32) | HSD11B1ALOX5AP | |
| SCHEMBL31333039 | 0.72 | HSD11B1 (0.48) | HSD11B1ALDH1A1 | |
| SCHEMBL441423 | 0.70 | ALOX15 (0.40) | HSD11B1 | |
| SCHEMBL900016 | 0.70 | ALOX5AP (0.39) | LMNAHSD11B1ALOX5AP | |
| SCHEMBL13779595 | 0.69 | ALOX5AP (0.30) | ALOX5AP | |
| SCHEMBL13183136 | 0.69 | — | — | |
| SCHEMBL15223673 | 0.69 | HSD11B1 (0.34) | HSD11B1ALOX5AP | |
| SCHEMBL4449268 | 0.69 | GRIN2D (0.34) | HSD11B1ALOX5AP | |
| SCHEMBL13779594 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216141-A | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES | BENNER, STEVEN | 1993-06-01 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |