Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410194 | 0.94 | MEN1 (0.35) | MEN1KMT2AGAAGUSBLMNA | |
| SCHEMBL9523079 | 0.90 | MEN1 (0.33) | MEN1KMT2AGAAGUSBLMNA | |
| SCHEMBL9523236 | 0.86 | TP53 (0.38) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL9521366 | 0.86 | HTR3A (0.31) | MAPT | |
| SCHEMBL26942676 | 0.86 | — | — | |
| SCHEMBL26942545 | 0.86 | PPOX (0.32) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL10410416 | 0.85 | HTR7 (0.39) | MEN1KMT2AGAALMNA | |
| SCHEMBL9520570 | 0.85 | GAA (0.37) | GAALMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL26942736 | 0.85 | — | — | |
| SCHEMBL6336900 | 0.83 | BAZ2B (0.46) | GAAGUSBLMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |