SCHEMBL952118

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4547708	0.89	EPHX2 (0.39)	EPHX2LMNACA12CA2CA7
	SCHEMBL952944	0.87	LMNA (0.35)	EPHX2LMNAMAPTL3MBTL1MEN1
	SCHEMBL949988	0.85	ALDH1A1 (0.34)	EPHX2LMNAMAPTL3MBTL1MEN1
	SCHEMBL12332558	0.85	EPHX2 (0.34)	EPHX2LMNACA12CA2CA7
	SCHEMBL950178	0.82	LMNA (0.34)	EPHX2LMNAMAPTL3MBTL1MEN1
	SCHEMBL952700	0.81	ALDH1A1 (0.34)	EPHX2LMNAMAPTL3MBTL1MAPK1
	SCHEMBL2735070	0.80	ALDH1A1 (0.36)	EPHX2LMNAMAPTMEN1KMT2A
	SCHEMBL106195	0.80	EPHX2 (0.33)	EPHX2LMNAMAPTL3MBTL1MEN1
	SCHEMBL19214568	0.80	EPHX2 (0.33)	EPHX2LMNAMAPTL3MBTL1MAPK1
	SCHEMBL12914684	0.79	EPHX2 (0.35)	EPHX2CA12CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.