SCHEMBL952944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12058487	0.89	EPHX2 (0.37)	EPHX2ALDH1A1MEN1KMT2AMAPK1
	SCHEMBL949988	0.87	ALDH1A1 (0.34)	LMNAEPHX2ALDH1A1MEN1KMT2A
	SCHEMBL952118	0.87	EPHX2 (0.36)	LMNAEPHX2ALDH1A1MEN1KMT2A
	SCHEMBL12332558	0.86	EPHX2 (0.34)	LMNAEPHX2ALDH1A1MEN1KMT2A
	SCHEMBL952700	0.82	ALDH1A1 (0.34)	LMNAEPHX2ALDH1A1MAPTMAPK1
	SCHEMBL950046	0.82	LMNA (0.35)	LMNAEPHX2ALDH1A1MEN1KMT2A
	SCHEMBL106195	0.81	EPHX2 (0.33)	LMNAEPHX2ALDH1A1MEN1KMT2A
	SCHEMBL2735070	0.81	ALDH1A1 (0.36)	LMNAEPHX2ALDH1A1MEN1KMT2A
	SCHEMBL19214568	0.81	EPHX2 (0.33)	LMNAEPHX2ALDH1A1MAPTMAPK1
	SCHEMBL25968927	0.80	EPHX2 (0.43)	EPHX2ALDH1A1MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.