SCHEMBL4622249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10392132	0.77	CYP3A4 (0.39)	CYP3A4ALDH1A1LMNAKMT2ASMN1; SMN2
	Bromide SCHEMBL3387285	0.74	MAPT (0.44)	CYP3A4ALDH1A1LMNAKMT2ASMN1; SMN2
	SCHEMBL4622151	0.72	CNR2 (0.39)	CYP3A4ALDH1A1LMNASMN1; SMN2POLB
	SCHEMBL4622144	0.72	CNR2 (0.39)	CYP3A4ALDH1A1LMNASMN1; SMN2POLB
	SCHEMBL5068338	0.69	CYP3A4 (0.59)	CYP3A4ALDH1A1KMT2ASMN1; SMN2MEN1
	SCHEMBL4615637	0.67	MAPT (0.48)	CYP3A4ALDH1A1KMT2ASMN1; SMN2MEN1
	SCHEMBL13278595	0.66	CYP3A4 (0.54)	CYP3A4ALDH1A1LMNAKMT2AMEN1
	SCHEMBL8520543	0.65	CYP3A4 (0.48)	CYP3A4ALDH1A1KMT2ASMN1; SMN2MEN1
	SCHEMBL28662	0.65	CYP3A4 (1.00)	CYP3A4ALDH1A1KMT2ASMN1; SMN2MEN1
	SCHEMBL3034960	0.64	L3MBTL1 (0.60)	CYP3A4ALDH1A1SMN1; SMN2KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.