Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20266341 | 0.84 | PKM (0.47) | PKMDRD2ADRA1ADRD3MTNR1A | |
| SCHEMBL2314792 | 0.84 | DRD2 (0.44) | PKMDRD2ADRA1ADRD3MTNR1A | |
| SCHEMBL10824954 | 0.83 | PKM (0.46) | PKMDRD2ADRA1ADRD3MTNR1A | |
| SCHEMBL7382368 | 0.81 | DRD2 (0.49) | PKMDRD2ADRA1ADRD3MTNR1A | |
| SCHEMBL966680 | 0.80 | OPRM1 (0.51) | PKMMTNR1AMTNR1BTSHRLMNA | |
| SCHEMBL2679486 | 0.80 | KDM4E (0.52) | DRD2ADRA1ADRD3ALDH1A1KDM4E | |
| SCHEMBL4137357 | 0.79 | NAAA (0.58) | DRD2ADRA1ADRD3ALDH1A1NPC1 | |
| SCHEMBL2104344 | 0.79 | PKM (0.49) | PKMDRD2ADRA1ADRD3MTNR1A | |
| SCHEMBL22559963 | 0.79 | PKM (0.49) | PKMDRD2ADRA1ADRD3MTNR1A | |
| SCHEMBL16835726 | 0.79 | DRD2 (0.47) | PKMDRD2ADRA1ADRD3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397556-B1 | N-Phenyl amides, methods for their preparation and medicaments containing them | RHONE POULENC SANTE (FR) | 1993-10-20 | — | — | EP | disclosed |
| EP-0397556-A1 | N-Phenyl amides, methods for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-11-14 | — | — | EP | disclosed |