Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137357 | 0.87 | NAAA (0.58) | DRD2ADRA1ADRD3NPC1RAB9A | |
| SCHEMBL11180708 | 0.87 | POLB (0.45) | PKMNPC1RAB9AALDH1A1MTNR1A | |
| SCHEMBL11173411 | 0.87 | ALDH1A1 (0.42) | PKMNPC1RAB9AALDH1A1MTNR1A | |
| SCHEMBL966680 | 0.85 | OPRM1 (0.51) | PKMNPC1RAB9AALDH1A1MTNR1A | |
| SCHEMBL9521252 | 0.84 | ITGB3 (0.46) | PKMDRD2ADRA1ADRD3NPC1 | |
| SCHEMBL10824954 | 0.84 | PKM (0.46) | PKMDRD2ADRA1ADRD3NPC1 | |
| SCHEMBL28992840 | 0.84 | KMT2A (0.48) | NPC1RAB9AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL2679486 | 0.81 | KDM4E (0.52) | DRD2ADRA1ADRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11549831 | 0.80 | PKM (0.43) | PKMDRD2ADRA1ADRD3NPC1 | |
| SCHEMBL11190748 | 0.80 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185100-B2 | Methods for modulating taste receptors | MARS, INCORPORATED (US) | 2021-11-30 | — | — | US | disclosed |
| WO-2021183758-A1 | IMMUNOMODULATING UREA AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| US-20190021380-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2019-01-24 | — | — | US | disclosed |
| US-20180255813-A1 | METHODS FOR MODULATING TASTE RECEPTORS | MARS, INCORPORATED (US) | 2018-09-13 | — | — | US | disclosed |
| US-20180168208-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2018-06-21 | — | — | US | disclosed |