Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 1/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 15/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 15/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30655549 | 0.80 | CD74 (0.50) | CD74MIFCYP4F2CYP4A11NOTUM | |
| SCHEMBL933474 | 0.78 | PRKCI (0.57) | PLA2G10PLA2G2A | |
| SCHEMBL952137 | 0.77 | CTSV (0.52) | CD74MIFCYP4F2CYP4A11NOTUM | |
| SCHEMBL951718 | 0.77 | ROCK2 (0.50) | CTSVCTSLCTSBCTSS | |
| SCHEMBL934607 | 0.76 | EPHX2 (0.51) | — | |
| SCHEMBL22501782 | 0.75 | CD74 (0.57) | CD74MIFCYP4F2CYP4A11NOTUM | |
| SCHEMBL3660578 | 0.75 | CD74 (0.74) | CD74MIFCYP4F2CYP4A11NOTUM | |
| Hydrochloric Acid SCHEMBL20502146 | 0.75 | GRIA2 (0.58) | CD74MIFNOTUMCTSVCTSL | |
| Hydrochloric Acid SCHEMBL20502144 | 0.75 | GRIA2 (0.58) | CD74MIFNOTUMCTSVCTSL | |
| SCHEMBL17279815 | 0.73 | NOTUM (0.74) | CD74MIFNOTUMSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |