Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243696 | 0.82 | MAP2K3 (0.47) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL21336547 | 0.82 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7439224 | 0.79 | ATP4A (0.37) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9324010 | 0.78 | TP53 (0.44) | ALDH1A1MEN1KMT2ALMNARAB9A | |
| SCHEMBL27662263 | 0.78 | TP53 (0.41) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14736658 | 0.77 | ADORA3 (0.40) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL2378994 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10622534 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14564382 | 0.73 | DHODH (0.50) | MAP2K3ASIC3AURKAPARP1 | |
| SCHEMBL7439221 | 0.72 | MEN1 (0.35) | ALDH1A1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1332952-C | 4-substituted imidazole-2-thiones, 4-substituted imidazole-2-ones and related compounds and their use | ALLERGAN INC (US) | 2007-08-22 | — | — | CN | disclosed |
| CN-1671671-A | 4- (substituted cycloalkylmethyl) imidazole-2-thiones, 4- (substituted cycloalkenylmethyl) imidazole-2-thiones, 4- (substituted cycloalkylmethyl) imidazol-2-ones, and 4- (substituted cycloalkenylmethyl) imidazol-2-ones, and related compounds | ALLERGAN INC (US) | 2005-09-21 | — | — | CN | disclosed |
| CN-1093535-C | Imidazole derivative | SHIONOGI & CO (JP) | 2002-10-30 | — | — | CN | disclosed |
| CN-1158609-A | Imidazole derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | CN | disclosed |
| EP-0298196-B1 | IMIDAZOLE COMPOUNDS AND BIOCIDAL COMPOSITIONS COMPRISING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4995898-A | Imidazole compounds and biocidal composition comprising the same for controlling harmful organisms | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0298196-A1 | Imidazole compounds and biocidal compositions comprising the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |