Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521622 | 0.93 | TRPV4 (0.43) | TRPV4EPHX2TRPV1NPC1RAB9A | |
| SCHEMBL9672771 | 0.87 | ADRA1A (0.55) | EPHX2TRPV1NPC1RAB9ADHODH | |
| SCHEMBL9521395 | 0.78 | ADRA1A (0.41) | NPC1RAB9A | |
| SCHEMBL9521689 | 0.77 | POLB (0.45) | NPC1RAB9A | |
| SCHEMBL9521170 | 0.76 | SMN1; SMN2 (0.50) | EPHX2NPC1RAB9A | |
| SCHEMBL9674900 | 0.74 | ADRA1A (0.50) | RAB9A | |
| SCHEMBL8276360 | 0.73 | NPC1 (0.61) | EPHX2TRPV1NPC1RAB9APTGS1 | |
| SCHEMBL9674557 | 0.73 | ADRA1A (0.59) | NPC1RAB9A | |
| Isoprothiolane SCHEMBL71267 | 0.72 | ADRA1A (0.60) | NPC1RAB9A | |
| Isoprothiolane SCHEMBL8408577 | 0.72 | ADRA1A (0.60) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |