Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043610 | 0.84 | CNR2 (0.38) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL9523374 | 0.79 | P2RX7 (0.59) | ALDH1A1KMT2AGAATDP1EPHX2 | |
| SCHEMBL9019625 | 0.76 | KMT2A (0.36) | ALDH1A1KMT2AGAATDP1MAPT | |
| SCHEMBL9522240 | 0.76 | KMT2A (0.54) | ALDH1A1KMT2AGAATDP1CNR2 | |
| SCHEMBL9044341 | 0.73 | CNR2 (0.42) | ALDH1A1KMT2AGAATSHRNPSR1 | |
| SCHEMBL9125672 | 0.72 | ALDH1A1 (0.59) | ALDH1A1KMT2AGAATDP1KDM4E | |
| SCHEMBL9521787 | 0.72 | P2RX7 (0.43) | ALDH1A1KMT2AGAATDP1MAPT | |
| SCHEMBL9044489 | 0.71 | CNR2 (0.52) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL9123758 | 0.70 | ALDH1A1 (0.57) | ALDH1A1KMT2AGAATDP1KDM4E | |
| SCHEMBL19474859 | 0.70 | KMT2A (0.69) | ALDH1A1KMT2AGAATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |