SCHEMBL1389422

SCHEMBL1389422

NCCCC[C@H](N)C(=O)OC(=O)[C@@H](N)CC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.50
CPB2 Q96IY4 3/20 0.39
DPP7 Q9UHL4 9/20 0.39
DPP9 Q86TI2 6/20 0.39
DPP8 Q6V1X1 5/20 0.39
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
DPP4 P27487 3/20 0.36
RNPEP Q9H4A4 1/20 0.36
FAP Q12884 1/20 0.33
MMP2 P08253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20240364 0.89 GSR (0.61) GSRCPB2DPP7DPP9DPP8
SCHEMBL1404247 0.89 GSR (0.61) GSRCPB2DPP7DPP9DPP8
SCHEMBL344574 0.89 GSR (0.61) GSRCPB2DPP7DPP9DPP8
SCHEMBL680614 0.87 GSR (0.59) GSRCPB2DPP7DPP9DPP8
Hydrochloric Acid SCHEMBL3825519 0.87 GSR (0.59) GSRCPB2DPP7DPP9DPP8
Hydrochloric Acid SCHEMBL2099474 0.87 GSR (0.59) GSRCPB2DPP7DPP9DPP8
SCHEMBL2535190 0.86 GSR (0.50) GSRCPB2DPP7DPP9DPP8
SCHEMBL18263222 0.86 GSR (0.55) GSRCPB2DPP7DPP9DPP8
SCHEMBL3467172 0.86 GSR (0.50) GSRCPB2DPP7DPP9DPP8
SCHEMBL18263219 0.86 GSR (0.50) GSRCPB2DPP7DPP9DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321267-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US claimed
EP-4223319-A2 METHOD AND MOLECULES MedImmune, LLC (US) 2023-08-09 EP claimed
US-11266968-B2 Mineralizing biosurfactant used for nucleating silica THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-08 US claimed
EP-3046870-B1 SILICA MICRO- AND NANO-CAPSULES AND METHODS FOR MAKING THEM UNIV QUEENSLAND (AU) 2021-08-11 EP claimed
EP-3630732-A1 METHOD AND MOLECULES Medimmune, LLC (US) 2020-04-08 EP claimed
CN-110650947-A Methods and molecules 免疫医疗有限责任公司 2020-01-03 CN claimed
WO-2018218093-A1 METHOD AND MOLECULES MEDIMMUNE, LLC (US) 2018-11-29 WO claimed
WO-2003099322-A2 IL-11 DERIVATIVES AND THERAPEUTIC USES THEREOF ISIS INNOVATION LIMITED (GB) 2003-12-04 WO claimed
US-20230321267-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US disclosed
US-11759526-B2 Method and molecules MEDIMMUNE, LLC (US) 2023-09-19 US disclosed
EP-4223319-A2 METHOD AND MOLECULES MedImmune, LLC (US) 2023-08-09 EP disclosed
US-20220371973-A1 Method and Molecules MEDIMMUNE, LLC 2022-11-24 US disclosed
EP-3994115-A1 METHOD AND MOLECULES MedImmune, LLC (US) 2022-05-11 EP disclosed
EP-3046870-B1 SILICA MICRO- AND NANO-CAPSULES AND METHODS FOR MAKING THEM UNIV QUEENSLAND (AU) 2021-08-11 EP disclosed
WO-2007069068-A2 CELL PENETRATING PEPTIDE CONJUGATES FOR DELIVERING NUCLEIC ACIDS INTO CELLS DIATOS (FR) 2007-06-21 WO disclosed
EP-1220911-B1 P-GLYCOPROTEINS AND USES THEREOF BECTON DICKINSON CO (US) 2006-11-29 EP disclosed
US-20060241365-A1 Implantable Biosensor and Methods of Use Thereof WILLOW LABORATORIES, INC. 2006-10-26 US disclosed
US-6753177-B1 USED IN DRUG SCREENING FOR INHIBITORS OF DOG P-GLYCOPROTEIN (PGP) BECTON DICKINSON AND COMPANY 2004-06-22 US disclosed
EP-1220911-A2 P-GLYCOPROTEINS AND USES THEREOF GENTEST CORPORATION (US) 2002-07-10 EP disclosed
WO-2001023540-A2 P-GLYCOPROTEINS AND USES THEREOF GENTEST CORPORATION (US) 2001-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321267-A1 Method And Molecules PAICS, EPCAM, SQLE GSR 1413/4885CPB2 1185/4885DPP7 2428/4885
US-20220371973-A1 Method and Molecules VIP, LNPEP, IAPP GSR 3530/4885CPB2 54/4885DPP7 194/4885
US-11759526-B2 Method and molecules PAICS, EPCAM, SQLE GSR 1413/4885CPB2 1185/4885DPP7 2428/4885
US-11266968-B2 Mineralizing biosurfactant used for nucleating silica SGMS2, PHOSPHO1, SOST GSR 1900/4885CPB2 2465/4885DPP7 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.