Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520932 | 0.79 | ALDH1A1 (0.49) | P2RX7ALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL7572613 | 0.79 | P2RX7 (0.72) | P2RX7ALDH1A1KMT2AEPHX2 | |
| SCHEMBL9125662 | 0.76 | ALDH1A1 (0.57) | ALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL8381564 | 0.76 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL9522240 | 0.76 | KMT2A (0.54) | ALDH1A1GAAKMT2ATDP1EPHX2 | |
| SCHEMBL7571529 | 0.75 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL14160432 | 0.75 | P2RX7 (0.71) | P2RX7EPHX2 | |
| SCHEMBL31424200 | 0.75 | P2RX7 (0.76) | P2RX7 | |
| SCHEMBL7568670 | 0.75 | P2RX7 (0.71) | P2RX7ALDH1A1KMT2A | |
| SCHEMBL7570190 | 0.75 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |