Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EPHB3 | P54753 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523535 | 0.90 | POLB (0.47) | MAPTSMN1; SMN2EPHB3NPC1RAB9A | |
| SCHEMBL9524492 | 0.88 | KCNMA1 (0.46) | MAPTSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL9524442 | 0.87 | EPHB3 (0.54) | MAPTEPHB3NPC1RAB9AHIF1A | |
| SCHEMBL9524522 | 0.85 | ALDH1A1 (0.51) | MAPTSMN1; SMN2NPC1RAB9AHIF1A | |
| SCHEMBL9524344 | 0.85 | TMPRSS4 (0.51) | NPC1RAB9AHIF1ANPSR1GRIK1 | |
| SCHEMBL9525872 | 0.83 | P2RX1 (0.50) | MAPTSMN1; SMN2NPC1RAB9AHIF1A | |
| SCHEMBL9524620 | 0.81 | P2RX1 (0.52) | MAPTSMN1; SMN2NPC1RAB9AHIF1A | |
| SCHEMBL9525753 | 0.81 | KCNMA1 (0.57) | MAPTSMN1; SMN2NPC1RAB9AHIF1A | |
| SCHEMBL9524532 | 0.79 | S1PR4 (0.44) | MAPTSMN1; SMN2RAB9ANPSR1CYP2C19 | |
| SCHEMBL9523781 | 0.79 | KCNMA1 (0.54) | MAPTSMN1; SMN2NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4877859-A | HEAT RESISTANCE, WATER RESISTANCE; PACKAGING | DAIKIN INDUSTRIES, LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0284993-A2 | Fluorine-containing novolak resin and derivative thereof | DAIKIN INDUSTRIES, LIMITED (JP) | 1988-10-05 | — | — | EP | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |