Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524160 | 0.86 | HIF1A (0.57) | ALDH1A1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL9524492 | 0.85 | KCNMA1 (0.46) | ALDH1A1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL9523476 | 0.85 | MAPT (0.47) | ALDH1A1MAPTRAB9ANPC1GRIK1 | |
| SCHEMBL9524714 | 0.81 | NPC1 (0.56) | ALDH1A1MAPTRAB9ANPC1GRIK1 | |
| SCHEMBL9523535 | 0.81 | POLB (0.47) | ALDH1A1MAPTRAB9ANPC1KCNMA1 | |
| SCHEMBL9524344 | 0.80 | TMPRSS4 (0.51) | ALDH1A1RAB9ANPC1GRIK1KDM4E | |
| SCHEMBL9524532 | 0.77 | S1PR4 (0.44) | MAPTRAB9AKCNMA1SMN1; SMN2TSHR | |
| SCHEMBL14567633 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL9524620 | 0.76 | P2RX1 (0.52) | ALDH1A1MAPTRAB9ANPC1HIF1A | |
| SCHEMBL9525872 | 0.76 | P2RX1 (0.50) | ALDH1A1MAPTRAB9ANPC1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |