Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 5/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524620 | 0.90 | P2RX1 (0.52) | P2RX1P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL9524344 | 0.88 | TMPRSS4 (0.51) | TMPRSS4MEN1KMT2AHIF1ARAB9A | |
| SCHEMBL9523781 | 0.87 | KCNMA1 (0.54) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9525148 | 0.86 | FADS1 (0.46) | P2RX1P2RX4P2RX7TMPRSS4MEN1 | |
| SCHEMBL9524408 | 0.86 | P2RX1 (0.53) | P2RX1P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL9525061 | 0.84 | RAB9A (0.51) | P2RX1P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL9523476 | 0.83 | MAPT (0.47) | MEN1KMT2AHIF1AMAPTRAB9A | |
| SCHEMBL9527668 | 0.83 | KCNMA1 (0.58) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9524888 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9525673 | 0.80 | MAOB (0.50) | P2RX1P2RX4P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | disclosed |
| US-4826837-A | IMMUNOMODULATORS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-05-02 | — | — | US | disclosed |
| EP-0277791-A2 | Cinnoline-carboxamides and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-08-10 | — | — | EP | disclosed |