Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922270 | 0.71 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL449614 | 0.68 | TSHR (0.43) | TDP1ALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL28999979 | 0.67 | CACNA2D1 (0.42) | TDP1ALDH1A1TSHRLMNATHRB | |
| SCHEMBL10583869 | 0.65 | TDP1 (0.43) | TDP1ALDH1A1TSHRLMNATHRB | |
| SCHEMBL4621245 | 0.64 | TDP1 (0.58) | TDP1ALDH1A1TSHRLMNATHRB | |
| SCHEMBL3121931 | 0.64 | SMN1; SMN2 (0.39) | TDP1ALDH1A1TSHRLMNATHRB | |
| SCHEMBL9524079 | 0.64 | KCNH3 (0.39) | ALDH1A1TSHRALOX12KMT2AMAPT | |
| SCHEMBL29985077 | 0.63 | GRM5 (0.42) | TDP1ALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL31026521 | 0.63 | NPC1 (0.49) | TDP1ALDH1A1TSHRLMNATHRB | |
| SCHEMBL28134028 | 0.63 | ALDH1A1 (0.41) | TDP1ALDH1A1TSHRLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5025105-A | — | — | None | — | — | JP | disclosed |
| JP-H0525105-A | N-METHOXYBUTYNYLANILINE DERIVATIVE AND ITS PRODUCTION | CENTRAL GLASS CO LTD | 1993-02-02 | — | — | JP | disclosed |