Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229386 | 0.90 | ALDH1A1 (0.49) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL9445071 | 0.89 | TSHR (0.47) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL26343371 | 0.88 | ITGA4 (0.48) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL863466 | 0.86 | GPR35 (0.51) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL19605560 | 0.86 | APP (0.48) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL9445058 | 0.86 | APP (0.45) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL51277 | 0.83 | GPR35 (0.60) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL4232672 | 0.82 | ITGA4 (0.49) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL216753 | 0.81 | GPR35 (0.58) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL4231830 | 0.81 | ALDH1A1 (0.58) | GPR35ALDH1A1TSHRTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395837-B1 | OXIDATION HAIR DYES BASED ON 4-AMINOPHENOL DERIVATIVES AS WELL AS NEW 4-AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 1993-04-14 | — | — | EP | disclosed |
| US-4997451-A | Developers | WELLA AKTIENGESELLSCHAFT (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0395837-A1 | Oxidation hair dyes based on 4-aminophenol derivatives as well as new 4-aminophenol derivatives | Wella Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |