Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.41 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.41 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523603 | 0.84 | NPC1 (0.45) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9525703 | 0.83 | RAB9A (0.43) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9527660 | 0.81 | ALDH1A1 (0.50) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9524797 | 0.80 | NPC1 (0.56) | RAB9ANPC1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9523753 | 0.80 | KMT2A (0.43) | RAB9ANPC1KMT2APOLBMAPT | |
| SCHEMBL9525788 | 0.79 | ALDH1A1 (0.49) | RAB9ANPC1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9524920 | 0.78 | KDM4E (0.46) | RAB9ANPC1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9524514 | 0.77 | KDM4E (0.42) | RAB9ANPC1KMT2APOLBMAPT | |
| SCHEMBL9525680 | 0.76 | HTT (0.43) | RAB9AKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9527795 | 0.76 | POLB (0.44) | RAB9ANPC1POLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |