Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527795 | 0.91 | POLB (0.44) | HTTALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL9524999 | 0.89 | RAB9A (0.44) | ALDH1A1GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9524812 | 0.87 | RAB9A (0.47) | ALDH1A1GAAKDM4ERECQLKMT2A | |
| SCHEMBL9527700 | 0.86 | DDX3X (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL9527660 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9525725 | 0.86 | KMT2A (0.49) | ALDH1A1GAAKDM4EKMT2ARAB9A | |
| SCHEMBL9523908 | 0.86 | HPGD (0.46) | HTTALDH1A1MAPTTHRBRECQL | |
| SCHEMBL9525178 | 0.86 | NPC1 (0.43) | HTTALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL9524816 | 0.85 | MEN1 (0.41) | HTTALDH1A1SMN1; SMN2USP2MAPT | |
| SCHEMBL9524870 | 0.84 | CSF1R (0.45) | HTTALDH1A1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |