Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524514 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1RAB9ANPC1HTT | |
| SCHEMBL9523753 | 0.83 | KMT2A (0.43) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9523603 | 0.81 | NPC1 (0.45) | KDM4EALDH1A1RAB9ANPC1HTT | |
| SCHEMBL9523663 | 0.80 | KMT2A (0.53) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9524403 | 0.78 | RAB9A (0.47) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9525680 | 0.77 | HTT (0.43) | KDM4EALDH1A1RAB9AHTTMAPT | |
| SCHEMBL9527795 | 0.77 | POLB (0.44) | ALDH1A1RAB9ANPC1HTTMAPT | |
| SCHEMBL9524812 | 0.76 | RAB9A (0.47) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9525788 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9527660 | 0.75 | ALDH1A1 (0.50) | KDM4EALDH1A1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |