Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523910 | 0.91 | MEN1 (0.43) | KMT2AMEN1KDM4EHTTALDH1A1 | |
| SCHEMBL9523753 | 0.85 | KMT2A (0.43) | KMT2AMEN1KDM4EHTTALDH1A1 | |
| SCHEMBL9524816 | 0.84 | MEN1 (0.41) | KMT2AMEN1KDM4EHTTALDH1A1 | |
| SCHEMBL9524612 | 0.82 | MAPT (0.49) | KMT2AMEN1HTTALDH1A1HIF1A | |
| SCHEMBL9525680 | 0.81 | HTT (0.43) | KMT2AKDM4EHTTALDH1A1GAA | |
| SCHEMBL9523908 | 0.79 | HPGD (0.46) | KMT2AMEN1HTTALDH1A1HIF1A | |
| SCHEMBL9527795 | 0.78 | POLB (0.44) | HTTALDH1A1HIF1AMAPTPOLB | |
| SCHEMBL9524442 | 0.77 | EPHB3 (0.54) | KMT2AMEN1KDM4EEPHB3ALDH1A1 | |
| SCHEMBL9524514 | 0.77 | KDM4E (0.42) | KMT2AMEN1KDM4EHTTALDH1A1 | |
| SCHEMBL9524999 | 0.77 | RAB9A (0.44) | KMT2AMEN1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |