Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523908 | 0.90 | HPGD (0.46) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL9525680 | 0.85 | HTT (0.43) | KMT2AMAPTRAB9AUSP2HTT | |
| SCHEMBL9524758 | 0.84 | KMT2A (0.48) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL9527795 | 0.82 | POLB (0.44) | MAPTRAB9ANPSR1HTTALDH1A1 | |
| SCHEMBL9527921 | 0.81 | TMPRSS4 (0.42) | MEN1KMT2AMAPTRAB9AUSP2 | |
| SCHEMBL9524999 | 0.81 | RAB9A (0.44) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9525178 | 0.81 | NPC1 (0.43) | MEN1KMT2AMAPTRAB9AHTT | |
| SCHEMBL9525725 | 0.81 | KMT2A (0.49) | MEN1KMT2ARAB9AEGFRALDH1A1 | |
| SCHEMBL9527660 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9528013 | 0.81 | HPGD (0.46) | MEN1KMT2AMAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |