Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528013 | 0.91 | HPGD (0.46) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL9524816 | 0.90 | MEN1 (0.41) | MEN1KMT2AMAPTRAB9AHTT | |
| SCHEMBL9524848 | 0.86 | MEN1 (0.47) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL9525680 | 0.86 | HTT (0.43) | KMT2AMAPTRAB9AHTTALDH1A1 | |
| SCHEMBL9527660 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9525725 | 0.86 | KMT2A (0.49) | HPGDALOX15MEN1KMT2ANPC1 | |
| SCHEMBL9525178 | 0.86 | NPC1 (0.43) | HPGDMEN1KMT2AMAPTNPC1 | |
| SCHEMBL9527700 | 0.86 | DDX3X (0.44) | MAPTALDH1A1HDAC6THRBRECQL | |
| SCHEMBL9527921 | 0.84 | TMPRSS4 (0.42) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9525121 | 0.84 | FLT3 (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |