Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540401 | 0.83 | SOAT1 (0.41) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9526288 | 0.82 | F11 (0.36) | F11FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9370452 | 0.72 | FAAH (0.41) | F11FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9525207 | 0.71 | MAPK14 (0.43) | F11 | |
| SCHEMBL4069849 | 0.70 | F11 (0.39) | F11FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL2846531 | 0.69 | FAAH (0.43) | F11FAAH | |
| SCHEMBL9369648 | 0.69 | FAAH (0.40) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9737058 | 0.67 | F11 (0.37) | F11FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9736572 | 0.67 | F11 (0.37) | F11FAAH | |
| SCHEMBL4083512 | 0.67 | F11 (0.42) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001183-A1 | IMIDAZOLE DERIVATIVE AS ACAT INHIBITOR | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| EP-0523941-A1 | Imidazoles as ACAT inhibitor | RHONE-POULENC RORER LIMITED (GB) | 1993-01-20 | — | — | EP | disclosed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | disclosed |