Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525306 | 0.83 | F11 (0.34) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9539516 | 0.80 | SOAT1 (0.41) | SOAT1ACAT1ALDH1A1LMNAHTT | |
| SCHEMBL9526288 | 0.76 | F11 (0.36) | FAAHALDH1A1LMNASMN1; SMN2CNR1 | |
| SCHEMBL9565792 | 0.70 | SOAT1 (0.63) | SOAT1ACAT1ALDH1A1LMNACASP3 | |
| SCHEMBL3378259 | 0.70 | SOAT1 (0.63) | SOAT1ACAT1ALDH1A1LMNACASP3 | |
| SCHEMBL29972770 | 0.70 | SOAT1 (0.63) | SOAT1ACAT1ALDH1A1LMNACASP3 | |
| SCHEMBL9370452 | 0.67 | FAAH (0.41) | FAAHALDH1A1CNR1CNR2PLA2G4A | |
| SCHEMBL9525207 | 0.65 | MAPK14 (0.43) | ALDH1A1LMNA | |
| SCHEMBL29632252 | 0.65 | KDM4E (0.46) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL28452914 | 0.65 | NPC1 (0.44) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001183-A1 | IMIDAZOLE DERIVATIVE AS ACAT INHIBITOR | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| EP-0523941-A1 | Imidazoles as ACAT inhibitor | RHONE-POULENC RORER LIMITED (GB) | 1993-01-20 | — | — | EP | disclosed |