Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525306 | 0.82 | F11 (0.34) | F11FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL9525207 | 0.78 | MAPK14 (0.43) | F11NPC1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4069849 | 0.77 | F11 (0.39) | F11NPC1FAAHKDM4EALDH1A1 | |
| SCHEMBL9540401 | 0.76 | SOAT1 (0.41) | FAAHALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL9737058 | 0.74 | F11 (0.37) | F11NPC1FAAHKDM4EALDH1A1 | |
| SCHEMBL9737053 | 0.74 | F11 (0.37) | F11NPC1FAAHKDM4EALDH1A1 | |
| SCHEMBL9736572 | 0.74 | F11 (0.37) | F11NPC1FAAHKDM4EALDH1A1 | |
| SCHEMBL2846531 | 0.74 | FAAH (0.43) | F11NPC1FAAHKDM4EMEN1 | |
| SCHEMBL9736574 | 0.74 | F11 (0.37) | F11NPC1FAAHKDM4EALDH1A1 | |
| SCHEMBL9370452 | 0.73 | FAAH (0.41) | F11NPC1FAAHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001183-A1 | IMIDAZOLE DERIVATIVE AS ACAT INHIBITOR | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| EP-0523941-A1 | Imidazoles as ACAT inhibitor | RHONE-POULENC RORER LIMITED (GB) | 1993-01-20 | — | — | EP | disclosed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | disclosed |