Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454085 | 0.88 | PPARG (0.56) | THRATHRBHDAC3HDAC1HDAC2 | |
| SCHEMBL10269078 | 0.87 | LMNA (0.59) | LMNAMAPTL3MBTL1THRATHRB | |
| SCHEMBL4304885 | 0.87 | HDAC3 (0.54) | MAPTL3MBTL1THRATHRBALDH1A1 | |
| SCHEMBL13926713 | 0.86 | THRA (0.61) | LMNASMN1; SMN2MAPTL3MBTL1THRA | |
| SCHEMBL4304889 | 0.84 | PPARG (0.55) | SMN1; SMN2THRATHRBPOLBHDAC3 | |
| SCHEMBL7497130 | 0.84 | KDM4E (0.61) | LMNAMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL7566083 | 0.84 | MAPT (0.52) | LMNASMN1; SMN2MAPTL3MBTL1POLB | |
| SCHEMBL30991357 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2MAPTL3MBTL1POLB | |
| SCHEMBL4556782 | 0.84 | CYSLTR2 (0.51) | LMNASMN1; SMN2MAPTL3MBTL1THRA | |
| SCHEMBL28382637 | 0.83 | MAPT (0.54) | LMNASMN1; SMN2MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |