Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525514 | 0.86 | KDM4E (0.50) | L3MBTL1MAPK1ALDH1A1HTTHIF1A | |
| SCHEMBL8418865 | 0.83 | MEN1 (0.50) | L3MBTL1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL4981784 | 0.82 | ALDH1A1 (0.61) | L3MBTL1MAPK1ALDH1A1POLB | |
| SCHEMBL9329169 | 0.81 | KDM4E (0.69) | SMN1; SMN2L3MBTL1MAPK1ALDH1A1MAPT | |
| SCHEMBL5115761 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2L3MBTL1MAPK1ALDH1A1HTT | |
| SCHEMBL9417984 | 0.80 | CNR2 (0.53) | SMN1; SMN2L3MBTL1MAPK1ALDH1A1MAPT | |
| SCHEMBL9528336 | 0.80 | MRGPRX4 (0.53) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL9417845 | 0.80 | CNR2 (0.50) | L3MBTL1MAPK1LMNACNR2CNR1 | |
| SCHEMBL9417815 | 0.79 | PLA2G2D (0.51) | L3MBTL1MAPK1ALDH1A1CNR2CNR1 | |
| SCHEMBL9417954 | 0.79 | PLA2G2D (0.51) | L3MBTL1MAPK1ALDH1A1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |