Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705823 | 1.00 | CYP2A6 (0.48) | CYP2A6GPR3MEN1KMT2ALMNA | |
| SCHEMBL19961736 | 0.86 | PARP14 (0.51) | CYP2A6GPR3MEN1KMT2ALMNA | |
| SCHEMBL31689733 | 0.86 | CYP2A6 (0.50) | CYP2A6MEN1KMT2ALMNATHRB | |
| SCHEMBL2786309 | 0.86 | CYP2A6 (0.50) | CYP2A6MEN1KMT2ALMNATHRB | |
| SCHEMBL9540651 | 0.81 | CYP2A6 (0.46) | CYP2A6GPR3MEN1KMT2ALMNA | |
| SCHEMBL9778942 | 0.81 | CYP2A6 (0.49) | CYP2A6MEN1KMT2ALMNATHRB | |
| SCHEMBL17454809 | 0.81 | GPR3 (0.48) | CYP2A6GPR3MEN1KMT2ALMNA | |
| SCHEMBL3057151 | 0.81 | GPR3 (0.48) | CYP2A6GPR3MEN1KMT2APARP14 | |
| SCHEMBL8149795 | 0.79 | CYP2A6 (0.43) | CYP2A6GPR3MEN1KMT2ALMNA | |
| SCHEMBL25165131 | 0.78 | GPR3 (0.45) | GPR3MEN1KMT2ALMNAPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250189532-A1 | 1,6-DIYNE COMPOUND, ITS PREPARATION METHOD, AND PRODUCTS OBTAINED USING 1,6-DIYNE COMPOUND AS RAW MATERIAL AND THEIR APPLICATIONS | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2025-06-12 | — | — | US | disclosed |
| CN-116730882-B | Structure of 1, 6-diyne compound and application thereof | 中国科学院福建物质结构研究所 | 2025-05-13 | — | — | CN | disclosed |
| EP-4488262-A1 | 1,6-DIYNE COMPOUND AND PREPARATION METHOD THEREFOR, AND PRODUCT OBTAINED USING 1,6-DIYNE COMPOUND AS RAW MATERIAL AND USE THEREOF | Fujian Institute Of Research On The Structure Of Matter, Chinese Academy Of Sciences (CN) | 2025-01-08 | — | — | EP | disclosed |
| WO-2024010732-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINE TRANSPORTER ASCT2 AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-01-11 | — | — | WO | disclosed |
| US-20230416422-A1 | COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE, POLYMER, AND METHOD FOR MANUFACTURING POLYMER | JSR CORPORATION (JP) | 2023-12-28 | — | — | US | disclosed |
| CN-116730882-A | Structure of 1, 6-diyne compound and application thereof | 中国科学院福建物质结构研究所 | 2023-09-12 | — | — | CN | disclosed |
| WO-2023165217-A1 | 1,6-DIYNE COMPOUND AND PREPARATION METHOD THEREFOR, AND PRODUCT OBTAINED USING 1,6-DIYNE COMPOUND AS RAW MATERIAL AND USE THEREOF | 中国科学院福建物质结构研究所 | 2023-09-07 | — | — | WO | disclosed |
| US-20230192695-A1 | THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS | UNIV ARIZONA STATE (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192695-A1 | THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS | UNIV ARIZONA STATE (US) | 2023-06-22 | — | — | US | disclosed |
| CN-111763208-B | Luminescent material and application thereof | 北京鼎材科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20150031686-A1 | PHENYL-OXAZOLYL DERIVATIVES, PREPARATION METHOD THEREOF, AND RELATED APPLICATION OF THE PHENYL-OXAZOLYL DERIVATIVES AS AN IMPDH INHIBITOR | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2015-01-29 | — | — | US | disclosed |
| EP-0183439-B1 | POLYCYCLIC COMPOUNDS, THEIR PREPARATION AND USE AND FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-02-03 | — | — | EP | disclosed |
| US-5075455-A | Microbiocides, antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-12-24 | — | — | US | disclosed |
| US-5049581-A | Dibenzofurans having anti-tumor activity | BURROUGHS WELLCOME CO. (US) | 1991-09-17 | — | — | US | disclosed |
| US-5017600-A | Antitumor | BURROUGHS WELLCOME CO. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5008286-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4970227-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4965285-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-10-23 | — | — | US | disclosed |
| US-4866070-A | ANTITUMOR AGENT | BURROUGHS WELLCOME CO. (US) | 1989-09-12 | — | — | US | disclosed |
| EP-0183439-A2 | Polycyclic compounds, their preparation and use and formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250189532-A1 | 1,6-DIYNE COMPOUND, ITS PREPARATION METHOD, AND PRODUCTS OBTAINED USING 1,6-DIYNE COMPOUND AS RAW MATERIAL AND THEIR APPLICATIONS | HAO2, HAO1, TH | CYP2A6 369/4885GPR3 737/4885MEN1 2755/4885 |
| US-20230192695-A1 | THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS | TTPA, TTC14, AAAS | CYP2A6 3780/4885GPR3 4053/4885MEN1 2254/4885 |
| US-20150031686-A1 | PHENYL-OXAZOLYL DERIVATIVES, PREPARATION METHOD THEREOF, AND RELATED APPLICATION OF THE PHENYL-OXAZOLYL DERIVATIVES AS AN IMPDH INHIBITOR | IMPDH1, IMPDH2, IMPA1 | CYP2A6 668/4885GPR3 4502/4885MEN1 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.