Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525669 | 0.87 | NPC1 (0.44) | NPC1RAB9APKMTP53KMT2A | |
| SCHEMBL9525703 | 0.87 | RAB9A (0.43) | NPC1RAB9APKMTP53KMT2A | |
| SCHEMBL9523603 | 0.86 | NPC1 (0.45) | NPC1RAB9APKMTP53KMT2A | |
| SCHEMBL9524933 | 0.85 | NPC1 (0.48) | NPC1RAB9APKMHPGDMITF | |
| SCHEMBL9527921 | 0.84 | TMPRSS4 (0.42) | GRIK1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9524819 | 0.83 | SORT1 (0.47) | NPC1RAB9AHPGDTP53KMT2A | |
| SCHEMBL9528013 | 0.81 | HPGD (0.46) | NPC1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL9525753 | 0.81 | KCNMA1 (0.57) | KCNMA1GRIK1NPC1RAB9AHPGD | |
| SCHEMBL9524939 | 0.78 | MEN1 (0.48) | GRIK1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL9527538 | 0.77 | KMT2A (0.47) | GRIK1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |