Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525703 | 0.87 | RAB9A (0.43) | NPC1RAB9APKMGAAKMT2A | |
| SCHEMBL9525903 | 0.87 | KCNMA1 (0.48) | NPC1RAB9ALMNAPKMGAA | |
| SCHEMBL9523603 | 0.86 | NPC1 (0.45) | NPC1RAB9ALMNAPKMGAA | |
| SCHEMBL9524933 | 0.85 | NPC1 (0.48) | NPC1RAB9ALMNAPKMGAA | |
| SCHEMBL9524870 | 0.84 | CSF1R (0.45) | NPC1RAB9ADHODHGAAKMT2A | |
| SCHEMBL9524868 | 0.83 | RAB9A (0.46) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL9525091 | 0.81 | RAB9A (0.41) | NPC1RAB9AGAAKMT2ASMN1; SMN2 | |
| SCHEMBL9527689 | 0.81 | NPC1 (0.46) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL9524715 | 0.81 | MEN1 (0.43) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL9524848 | 0.77 | MEN1 (0.47) | NPC1RAB9ALMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |