Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524939 | 0.92 | MEN1 (0.48) | HPGDALOX15MAPTMEN1KMT2A | |
| SCHEMBL9527921 | 0.92 | TMPRSS4 (0.42) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL9524848 | 0.91 | MEN1 (0.47) | HPGDALOX15MAPTMEN1KMT2A | |
| SCHEMBL9524849 | 0.91 | ALDH1A1 (0.46) | HPGDALOX15MAPTMEN1KMT2A | |
| SCHEMBL9523908 | 0.91 | HPGD (0.46) | HPGDALOX15MAPTMEN1KMT2A | |
| SCHEMBL9527538 | 0.85 | KMT2A (0.47) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL9524715 | 0.83 | MEN1 (0.43) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL9524819 | 0.81 | SORT1 (0.47) | HPGDMAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL9524816 | 0.81 | MEN1 (0.41) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL9525903 | 0.81 | KCNMA1 (0.48) | HPGDALOX15MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |