Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 5/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527463 | 0.79 | LCK (0.38) | LIPEGAANPC1RAB9AKMT2A | |
| SCHEMBL1694615 | 0.73 | LMNA (0.42) | LIPEGAALMNAL3MBTL1NPC1 | |
| SCHEMBL243237 | 0.73 | RAB9A (0.48) | LIPELMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL9523603 | 0.72 | NPC1 (0.45) | KDM4EGAALMNAL3MBTL1NPC1 | |
| SCHEMBL761922 | 0.71 | ALOX15 (0.45) | LIPEKDM4ELMNAL3MBTL1NPC1 | |
| SCHEMBL9524920 | 0.69 | KDM4E (0.46) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL9524918 | 0.68 | RAD52 (0.42) | KDM4EGAALMNAKMT2A | |
| SCHEMBL31323064 | 0.68 | NCEH1 (0.48) | LIPEKDM4ELMNAL3MBTL1NPC1 | |
| SCHEMBL25081069 | 0.67 | LIPE (0.47) | LIPEGAALMNANPC1RAB9A | |
| SCHEMBL16415718 | 0.67 | LMNA (0.47) | LIPEKDM4EGAALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |